• Supports ECG and respiration impedance measurement; configurable as 2-channel ECG or 1-channel ECG + 1-channel respiration
• Can be used in IEC 60601-2-47:2012/(R)2016 and IEC 60601-2-27:2011(R)2016 compliant systems
• 222 μA/channel while operating as 2-channel ECG
• Integrated Pace pulse detection on 1 channel
• Supports a 3-lead ECG, extendable to 5 leads or higher by operating two or more AFEs in parallel
• PPG signal chain for SpO2, Heart rate and PTT
• ECG signal chain:
  • Single channel ECG acquisition up to 2.048 kHz
  • 2 channel ECG acquisition up to 1.36 kHz/channel
  • RLD output to set body bias through third electrode
  • Programmable INA gain from approximately 2 to 12
  • >1 GΩ input impedance, CMRR > 100 dB
  • Input noise (0.5-150 Hz): 13 µVpp at INA gain of 3; 5 μVpp at INA gain of 12
  • Integrated 370 Hz anti-aliasing low pass filter
  • Mode for continuous lead on/off detection
  • Mode for lead impedance measurement
• Bio-Z signal chain:
  • Measurement of Bio-impedance over excitation frequency from 30 kHz to 100 kHz
  • Sine wave or square wave excitation
  • Respiration impedance measurement: 45 mΩ-pp noise on a baseline impedance of 2 kΩ
• Dual channel ECG channel:
  • Bio-Z receiver configurable as a 2^nd ECG channel
• PPG Signal Chain
  • Supports acquisition of up to 24 PPG signals
  • Flexible allocation of 4 LED, 4 PD in each phase
  • 8-Bit LED Current control up to 250 mA
  • Low noise current DAC at input to cancel DC
  • Trans-impedance Gain: 3.7 kΩ to 1 MΩ
  • Filter to reduce sensor’s optical noise bandwidth
• External clock and internal oscillator modes
• FIFO with 128-sample Depth, 24-bit word
• SPI^TM, I²C interfaces: Selectable by pin
• 2.6-mm × 2.6-mm DSBGA, 0.4-mm Pitch
• Supplies: Rx:1.7-1.9 V, I_O:1.7-1.9 V, Tx: 3.0-5.5 V

• Wireless patches for in-patient and out-patient monitoring
• Event monitors for arrhythmia detection
• Hand-held ECG monitor
• Portable multi-lead ECG
• Patient vital sign monitoring: holter, event, stress and telemedicine
• SpO2 & Heart rate, and PTT-based blood pressure through synchronized ECG, PPG

The AFE4960P supports synchronized signal acquisition of ECG, PPG and bio-impedance signals. A PPG signal chain comprises of a current driver for LEDs and a receiver that senses the signal from PDs. The AFE can be configured as either a 2-channel ECG receiver or as a 1-channel ECG receiver and a Respiration impedance channel. The AFE signal chains can interface in a flexible manner to up to 4 electrodes. The AFE has AC and DC Lead biasing and lead on/off detection. Pacemaker pulse detection is supported on one channel. All the signal chain outputs are converted by a single ADC in well-defined time slots and stored as 24-bit words in a 128-sample FIFO which can be read out using a SPI or an I²C interface. The AFE4960P can be used to realize a 3-lead ECG system along with SpO2.