The OPAx388-Q1 zero-drift amplifiers are engineered with the unique combination of a proprietary precision auto-calibration technique and a low-noise, low-ripple, input charge pump. These amplifiers offer ultra-low input offset voltage and drift and achieve excellent input and output dynamic linearity. The OPAx388-Q1 operate from 2.5 V to 5.5 V, are unity-gain stable, and are designed for a wide range of general-purpose and precision applications. The integrated, low-noise charge pump allows true rail-to-rail input common-mode operation without distortion associated with complementary rail-to-rail input topologies (input crossover distortion). The OPAx388-Q1 strengths also include 10-MHz bandwidth, 7-nV/√ Hz noise spectral density, and no 1/f noise, making these devices an excellent choice for interfacing with sensor modules and buffering high-fidelity digital-to-analog converters (DACs).