Many industrial applications require systems to operate 24 hours a day and seven days a week for several years. To keep those industrial systems in operation, it is important to be able to predict the wear-out of the systems so the equipment can be serviced and maintained to try to prevent a failure during normal operation. The semiconductor devices that are designed into those systems have typically been expected to reach estimated lifetimes of 100k POH at maximum junction temperature (T_j). Now, with a demand for reduced maintenance, industrial systems must meet even longer operational lifetimes. To help facilitate this at the semiconductor component level, this document details the requirements and limitations to extend the estimated operational lifetime of the AM64x processor and AM243x microcontroller from 100k POH up to 200k POH.