Transimpedance Amplifier (TIA) is a dedicated amplifier mode used to convert current signals into voltage signals widely applied in photodetection, sensor interfaces, and other applications requiring high sensitivity. These applications place great emphasis on the multifunctionality and scalability of microcontrollers (MCU), as well as low power consumption and integrated functions that can reduce system size. In the future, many sensing applications can exhibit a wide diversity, with each application having a unique set of functions and system resources. Designers can increasingly turn to highly integrated, yet multifunctional low-power microcontrollers, such as the MSPM0L134x MCU, to simplify system design and expedite time-to-market.