ISOUSB111 is a galvanically-isolated USB2.0 compliant repeater supporting Low Speed (1.5 Mbps) and Full Speed (12 Mbps) signaling rates. The device supports automatic speed and connection detection, reflection of pull-ups/pull-downs, and link power management allowing drop-in USB hub, host, peripheral and cable isolation. Most microcontrollers integrate the USB PHY, and so offer only D+ and D- bus lines as external pins. ISOUSB111 can isolate these pins from the USB bus without needing any other intervention from the microcontroller. The device also supports automatic role reversal - if after disconnect, if a new connect is detected on the Upstream facing port, then the Upstream and Downstream port definitions are reversed.

ISOUSB111 is available in reinforced isolation option with isolation withstand voltage of 5000 V_RMS respectively, and with surge test voltage of 12.8 kV_PK respectively. The device can operate completely off a 4.25 V to 5.5 V supply (USB VBUS power) or from local 3.3-V supply, if available, on both side 1 and side 2. This flexibility in supply voltages allows optimization for thermal performance based on power rails available in the system.