Proper design, layout, shielding, and environment control measures help to minimize the impact of these factors and maintain the calibration of a high-speed ADC for a longer period of time. By implementing robust design measures, such as proper grounding, shielding techniques, and thermal management, the adverse effects of temperature variations, external factors, and mechanical stress or vibration can be mitigated. These measures help ensure the long-term accuracy and performance of high-speed ADCs, optimizing their functionality within digital systems and reducing the need for frequent re-calibration.