The MSPM0 C-series microcontroller (MCU) portfolio offers a wide variety of low cost 32-bit MCUs with ultra-low-power and integrated analog and digital peripherals for sensing, measurement and control applications. This application note covers information needed for hardware development with MSPM0 C-series MCUs, including detailed hardware design information for power supplies, reset circuitry, clocks, debugger connections, key analog peripherals, communication interfaces, GPIOs, and board layout guidance.