Like the GPIO pins, the analog peripherals offer flexible pin usage. Buffered DAC outputs, CMPSS inputs, PGA functions, and digital inputs are multiplexed with ADC inputs. Furthermore, all ADCs have an internal connection to VREFLO allowing for offset self-calibration.

When choosing analog pin connections, take into consideration the peripherals available on each pin. Analog inputs with comparators allow for those analog signals to be able to quickly trip PWMs (as a fault signal) or to detect zero-crossing. Because these devices contain multiple ADCs, also consider if sampling certain analog signals simultaneously is beneficial. In these situations, three simultaneous analog signals could be connected to ADC-A, ADC-B, and ADC-C.

The F2800x devices feature varying numbers of digital GPIOs multiplexed with analog pins. These are known as AIOs and AGPIOs. All of the F2800x devices feature AIOs, which are multiplexed analog pins that can only function in input mode. By default, they will function as analog pins while the GPIOs are in a high-impedance (high-Z) state. A new type of analog pin is the AGPIO. These are available on F28003x and F280013x, which feature both AIOs and AGPIOs. These AGPIOs function similarly to AIOs except that they offer full input and output capabilities. By default, the AGPIOs are not connected and have to be configured. Note that if digital signals with sharp edges are connected to the AIOs or AGPIOs, cross-talk can potentially occur on directly adjacent analog signals.